The Contact Guidance Biochip Depth Survey Kit is designed to allow rapid identification of groove geometries that provide greatest sensitivities to specific cell types and experimental conditions.
Each kit includes 3 slides: 1 ea. of 330 nm depth, 720 nm depth, and 1 μm depth Contact Guidance Biochips (#2 thickness).
act Guidance Biochips provide atomically smooth features at multiple depths that are known to dictate numerous forms of cell behavior from elongation to stem cell renewal.
Each Contact Guidance Biochip contains 4 duplicate arrays, with each array containing 8 unique patterned groove sets, enabling researchers access to robust data output per experiment. Grooves are etched, separated by gaps of 2.5 to 20 µm (in x) at depths of 330 nm, 720 nm, and 1 µm (in z).
Users can coat Contact Guidance Biochip with coating method of their choice such as fibronectin, laminin, etc.
Contact Guidance Biochips are offered in #1 and #2 thickness depending on experimental requirements of numerical aperture and magnification for imaging (#1 recommended if immersion medium is being used).
Anisotropic vertical etching of grooves creates clean features with near 90° angles
Multiplexed patterns per array and multiplexed array per chip enables robust data generation per experiment across several treatments
Lot-validated atomically smooth surfaces (Ra < 1 nm)
Navigation landmarks are etched on slide, allowing user to maintain orientation
Contact Guidance Biochips are lot validated by atomic force microscopy for average surface roughness (Ra) < 1 nm.
Storage & Handling:
Shipped sterile with desiccant
Store at room temperature
Handle with tweezers
330 nm depth, #1 glass [N2-33Q1-4]
330 nm depth, #2 glass [N2-33Q2-4]
720 nm depth, #1 glass [N2-72Q1-4]
720 nm depth, #2 glass [N2-72Q2-4]
1 µm depth, #1 glass [N2-1uQ1-4]
1 µm depth, #2 glass [N2-1uQ2-4]