Nanocrine Surface Chemistry Biochips guide cellular phenotypes through tunable ligand spacing, providing new tools for quantitative morphology assays and classification. The biochips are ready-to-use out of the packaging, reducing wasted time and effort, with surface quantification providing unparalleled reliability and reproducibility.
cRGD Surface Chemistry Biochips are functionalized with RGD-peptides, the fibronectin minimum binding motif, a receptor for several integrins including αVß3, α5ß1, and αIIbß3, thereby permitting integrin-mediated cellular adhesion to the substrate.
Ligand density explanation
- Self-assembled monolayer (SAM) chemistry is utilized to control precise spacing of mean distance between ligands enabling new phenotypic classification data capture in current workflows.
- These products represent a new threshold of a ready-to-use, reliable, and repeatable platform for cell microscopy experiments.