• Intelligent surface design.

    We leverage advanced fabrication techniques and unique chemistries that enable novel phenotyping capabilities relevant to pathogenesis, drug discovery, and other complex biological questions.

  • Ready-to-use.

    Devote time to what truly matters and minimize time wasted on sample preparation with products that are ready to use.

  • Custom surfaces and services.

    We are the leader in surface design through microfabrication techniques for in vitro platforms and functionalizing biosensors. Contact us for your project.

Surfaces for Cells

Despite landmark achievements, living cells are an enigma. Media components, molecular tools for gene editing, and bioassay detection tools have evolved significantly over the past decades. Cell culturing platforms, the surfaces that interface with cells and provide physical and chemical input, have been disproportionately neglected. Our products are designed to address a specific gap in technology to open new avenues of exploration and analysis resulting in novel assay development and unlocking unprecedented insights while accelerating the data acquisition process and enhancing reproducibility.

Applications

  • Serum-free cell culturing
    Serum-free cell culturing

    Animal-derived components such as fetal bovine serum add to the variables in your biological workflow. Nanocrine surface chemistry biochips support cell viability in the absence of FBS.

  • Rapid detection of altered motility-associated morphology
    Rapid detection of altered motility-associated morphology

    Reduce the time it takes to reveal morphological biomarkers associated with epithelial-mesenchymal-transition on Nanocrine Surface Chemistry Biochips. Label-free and fixation-free allows for in process decision making.

  • Culture cardiomyocytes with precision-defined surfaces
    Culture cardiomyocytes with precision-defined surfaces

    Surface-coating protocols for cell culture can be expensive and time consuming, and it can become an additional source of lab-to-lab variability. Our Surface Chemistry Biochips can fulfill the same need with a greater level of control and with none of the typical pitfalls.

  • Unmask and amplify phenotypes during viral infection
    Unmask and amplify phenotypes during viral infection

    Reveal novel phenotypes or amplify weakly altered morphology through the use of tunable surface technology.

Publications

  • Concurrent control technique
    A Concurrent Control Technique for Quantifying Surface Ligand Activity

    Surface ligand activity is a key design parameter for successfully interfacing surfaces with cells...

  • Concurrent control technique
    Monolithic quartz platform for cellular contact guidance

    Contact guidance is vital to many physiological processes, yet is still poorly understood...

  • Concurrent control technique
    Automated cell segmentation for reproducibility

    Live-cell imaging is extremely common in synthetic biology research, but its ability to be applied reproducibly...